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Paternal Age linked to Bipolar Disorder in Offspring

Posted by medliorator on September 3, 2008

Older fathers are more likely to have children with bipolar disorder, research suggests.

The risk goes up when men are older than 29 before they start their family, and is highest if they are over 55.

Increasing paternal age has already been linked with schizophrenia and autism, but not bipolar disorder, formerly known as manic depression.

The Swedish study, in Archives of Psychiatry, suggests the risk may, in part, be explained by ageing sperm.

The children of men 55 years and older were 1.37 times more likely to go on to be diagnosed with bipolar disorder than those of men aged 20 to 24.

Older fathers linked with bipolar [BBC]

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