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New Alzheimer’s Drug Targets Tau Tangles

Posted by medliorator on July 30, 2008

methylthioninium chloride, is the first treatment specifically designed to target the Tau tangles.

Other treatments for Alzheimer’s tend to focus on combating a waste protein in the brain, beta-amyloid, which is known to form hard plaques. The latest work suggests targeting Tau may produce better results.

Trials of the drug, known as Rember, in 321 patients showed an 81% difference in rate of mental decline compared with those not taking the treatment.

Larger trials of the drug are planned to start in 2009, and researchers are also investigating whether the drug has a role in prevention of the disease in the first place.

Alzheimer’s drug ‘halts’ decline [BBC]


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